My most anticipated game for 2012 already came out, and it was Kid Icarus: Uprising. It was WAY better than I thought it would be. Out of what's upcoming, I'd say Pokemon: Conquest, as it looks very interesting. I definitely want to try the Darksiders series, but I'd rather start with the first...
To me, Hyrule Castle in Twilight Princess was disappointing because all of the dungeons before it were long (except the Palace of Twilight), yet it was very short.
Seriously they need to make this. They say they want to make a new adventure in the series for the 3DS before they make another remake, but I hope they make this. I want MM 3D more than I want another new game, anyway.
Wow, I've a few, but I can't remember all of them. All I can think of is when I was playing Four Swords (original) with my friend, and he had to leave, so I had to defeat the Deguchitato by myslef, which is VERY hard with two GBAs and only one person.